We show that cellular Floer cohomology of an immersed Lagrangian brane is invariant under smoothing of a self-intersection point if the quantum valuation of the weakly bounding cochain vanishes and the Lagrangian has dimension at least two. The chain-level map replaces the two orderings of the self-intersection point with meridianal and longitudinal cells on the handle created by the surgery, and uses a bijection between holomorphic disks developed by Fukaya-Oh-Ohta-Ono... Our result generalizes invariance of potentials for certain Lagrangian surfaces in Dimitroglou-Rizell--Ekholm--Tonkonog, and implies the invariance of Floer cohomology under mean curvature flow with this type of surgery, as conjectured by Joyce. (read more)